
Latest [Sep 24, 2021] BPS BPS-Pharmacotherapy Exam Practice Test To Gain Brilliante Result
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NEW QUESTION 71
Which statement regarding vaccine administration in infants and children is correct?
- A. The appropriate administration site is the deltoid.
- B. The vaccines may be combined in the same syringe.
- C. Live Vaccines should be administered at least 2 Weeks before killed Vaccines in infants less than 6 months old.
- D. There is no limit to the number of vaccines an individual may receive at one visit.
Answer: A
NEW QUESTION 72
To correct the development of metabolic acidosis in patients receiving standard TPN solutions, which of the following is the best therapeutic intervention?
- A. Decrease the potassium and increase the calcium.
- B. Hyperventilate the patient to produce hypocapnia.
- C. Decrease the chloride and increase the acetate.
- D. Decrease the phosphate and add bicarbonate.
Answer: D
NEW QUESTION 73
According to the Centers for Disease Control and Prevention recommendations, administration of which vaccines must be separated by at least 4 weeks if the vaccines are not administered simultaneously?
- A. Measles, mumps, and rubella (MMR), and Haemophilus influenzae type b (Hib)
- B. Tetanus/diphtheria (Td) and hepatitis A
- C. Measles, mumps, and rubella (MMR), and varicella
- D. Tetanus/diphtheria (Td) and intranasal influenza
Answer: A
NEW QUESTION 74
A new team has been established in a large healthcare system to conduct research. At the first meeting of the new team, the pharmacotherapy specialist was asked to submit a proposal for a randomized clinical study. What is the first step in formulating the research hypothesis for this proposal?
- A. Selecting an appropriate comparator
- B. Determining a measurable outcome
- C. Selecting a viable intervention
- D. Formulating an answerable question
Answer: D
NEW QUESTION 75
In which of the following scenarios should the error be reported to the Institute for Safe Medication Practices?
- A. A shipment of influenza vaccine was received by the pharmacy and was not placed in a refrigerator until the following day.
- B. A patient complains to a pharmacy manager that she did not receive an iPLEDGE brochure when receiving isotretinoin.
- C. A patient receives a 30-day supply of a prescription written for twice daily dosing with only 30 tablets dispensed.
- D. A pharmacy technician fills a prescription incorrectly with a "sound-alike" product, but the error is caught by the pharmacist before being dispensed to the patient.
Answer: B
NEW QUESTION 76
Which of the following sources is most likely to publish the current recommendations from the Centers for Disease Control and Prevention regarding the use of recombinant hepatitis B Vaccine?
- A. Medical Letter on Drugs and Therapeutics
- B. Morbidity and Mortality Weekly Report
- C. Journal of Hepatology
- D. Clinical Infectious Diseases
Answer: A
NEW QUESTION 77
A hospital's P & T Committee is considering whether a particular drug should be considered for therapeutic substitution. The pharmacotherapy specialist considers the acquisition cost of each medication and recommends using the drug with the lower cost. Which of the following types of analysis has the pharmacotherapy specialist used?
- A. Cost-benefit
- B. Cost-minimization
- C. Cost-effectiveness
- D. Cost-utility
Answer: B
NEW QUESTION 78
A 65-year-old man presents to the internal medicine clinic with decreased exercise tolerance, lower extremity edema, and shortness of breath.
He has a history of diastolic dysfunction (ejection fraction of 60%) and hypertension; BP =
150/90 mm Hg, HR = 86 bpm.
Current medications include digoxin 125 mcg daily, furosemide 40 mg daily, enalapril 10 mg twice daily, aspirin 325 mg daily, and potassium 10 mEq twice daily. The digoxin concentration is 0.4 ng/mL.
After resolution of this exacerbation, which of the following should the pharmacotherapy specialist recommend to the internist regarding this patient's maintenance drug therapy?
- A. Discontinue digoxin and add amlodipine.
- B. Increase furosemide.
- C. Discontinue digoxin and add metoprolol.
- D. Increase digoxin.
Answer: C
NEW QUESTION 79
A shortage of parenteral acyclovir was just announced; a hospital has 25 vials on hand and uses
20 vials in a typical month. The wholesaler has 250 vials on hand but will not receive any more supply for 4 months. What is the hospital's most appropriate response to the shortage?
- A. Obtain stock from a neighboring hospital when supplies run out.
- B. Develop guidelines for use of the remaining supply.
- C. Issue daily updates to prescribers on inventory levels.
- D. Order 250 vials in case the shortage is longer than expected.
Answer: B
NEW QUESTION 80
A 35-year-old Woman is diagnosed with pustular psoriasis, which covers 35% of her body. She has tried high-potency topical steroid creams and topical coal tar with ultraviolet B treatments in the past, with no effect. Which of the following is the best therapeutic option for this patient?
- A. Calcipotriene
- B. Methotrexate
- C. Halobetasol
- D. Anthralin
Answer: B
NEW QUESTION 81
Many clinically important adverse drug reactions (ADRs) are detected after the marketing of a drug, rather than during premarketing clinical trials. Of the following, which is the primary reason for this phenomenon?
- A. Too few patients are studied for too short a period of time during premarketing clinical trials.
- B. Pharmaceutical companies prefer to market agents with favorable side-effect profiles, so they focus premarketing studies on efficacy rather than on ADRs.
- C. Adverse reactions that are due to drug interactions or drug accumulation in renal insufficiency cannot be studied prospectively during the premarketing phase of clinical evaluation.
- D. Premarketing studies focus on efficacy rather than on safety; therefore, the study design accounts for the failure to detect ADRs.
Answer: A
NEW QUESTION 82
A pharmacy student on rotation in a community health clinic states that he saw medical charts outside exam rooms in the box on the door. He wants to know if this conforms to the Health Insurance Portability and Accountability Act (HIPAA) privacy rule. What is the best response?
- A. No, patient charts must be kept in a secure location at the nurses' station or in the room with the patient
- B. No, patient charts may not be placed outside an exam room door
- C. Yes, if the clinic removes the patient's name from the outside of the chart and places the chart in an unlabeled bin
- D. Yes, provided that the clinic takes reasonable and appropriate measures to protect the patient's privacy
Answer: B
NEW QUESTION 83
A 25-year-old woman who is HIV-positive and has a CD4+ count of 120 cells/mm begins antiretroviral therapy. The patient's CD4+ count drops to 45 cells/mm3 over the next year. For which of the following opportunistic infections should this patient receive prophylaxis?
- A. MAC and Pneumocystis jirovecii pneumonia
- B. Mycobacterium tuberculosis and Pneumocystis Jirovecii pneumonia
- C. MAC and Candida
- D. Mycobacterium tuberculosis and CMV
Answer: A
NEW QUESTION 84
Which is the most effective method to improve the safety of the use of phytonadione in an institution with a 24-hour pharmacy?
- A. Computer order sets that default to using a standardized number of vials or amps of phytonadione per dose
- B. Removal of phytonadione from all patient care areas of the facility coupled with strict usage guidelines
- C. Yearly in-service education and medical staff presentation about phytonadione use
- D. Establishment of emergency preparedness kits containing phytonadione to be stored in the patient care areas where warfarin is used
Answer: B
NEW QUESTION 85
A 42-year-old woman is diagnosed with deep vein thrombosis. Heparin therapy is initiated with
5,000 units as a single bolus injection, followed by an initial infusion rate of 1,000 units/h. The aPTT measured 6 hours later is >150 sec. Which of the following would be the most appropriate action at this time?
- A. Stop the infusion for one hour, then resume at 750 units/h.
- B. Stop the infusion until the aPTT falls to <50 sec, and then resume at 750 units/h.
- C. Administer protamine 5 mg, and decrease the infusion rate to 750 units/h.
- D. Continue the infusion at 1,000 units/h, since the aPTT was drawn too early and is not useful.
Answer: D
NEW QUESTION 86
A study of oral contraceptive use found a risk of breast cancer in long-term (> 12 years) higher dose oral contraceptive users odds ratio = 2.33 (95% CI = 0.9-3.2). Which of the following statements most accurately assesses the study's conclusion that there is a modest effect of oral contraceptive use on breast cancer risk in young women?
- A. The conclusion is justified statistically because the odds ratio is significant.
- B. The conclusion cannot be evaluated until the odds ratio is converted to relative risk.
- C. The conclusion is understated because the odds ratio is greater than two times the nonuser risk.
- D. The conclusion is not justified statistically because the odds ratio is nonsignificant.
Answer: D
NEW QUESTION 87
A 68-year-old female patient is admitted to the ICU for acute decompensated heart failure. She is currently intubated due to acute respiratory failure and hypoxia. After intubation, her Richmond Agitation-Sedation Scale (RASS) score is +3, and her Confusion Assessment Method for the ICU (CAM-ICU) is positive for delirium. She denies pain.
Which of the following is the best recommendation for achieving her sedation goal of RASS equals zero?
- A. Initiate propofol at 5 mcg/kg/min and titrate as needed.
- B. Administer lorazepam infusion at a rate of 1 mg/h.
- C. Initiate morphine 2 mg intravenously q6h as needed for delirium.
- D. Administer haloperidol 5 mg intravenously q4h as needed for delirium.
Answer: A
NEW QUESTION 88
A physician suspects that a patient's symptoms are related to abrupt discontinuation of a certain drug and asks the pharmacotherapy specialist about common reactions in this type of situation.
A literature search produces one case report of a discontinuation syndrome involving the drug.
What is the most appropriate action to take with regard to the current suspected adverse event?
- A. Report the event to the P & T Committee.
- B. Report the event to the FDA MedWatch program.
- C. Write and submit a case report detailing the event.
- D. Complete a manufacturer's adverse event report.
Answer: C
NEW QUESTION 89
A 59-year-old patient who is HIV-positive is receiving darunavir and ritonavir as part of a highly active antiretroviral therapy program. Which herbal supplement is contraindicated for this patient because it would decrease darunavir concentrations?
- A. Kava kava
- B. Saw palmetto
- C. Echinacea
- D. St. John's wort
Answer: D
NEW QUESTION 90
A patient with hepatic encephalopathy is being treated with lactulose 15 mL four times daily.
Over the next 72 hours, the patient becomes less agitated but remains disoriented. Which of the following should be the next step?
- A. Measure stool pH to ensure that it is greater than 7.
- B. Begin branched-chain amino-acid supplementation.
- C. Add neomycin 1 g four times daily.
- D. Determine the frequency of bowel movements.
Answer: C
NEW QUESTION 91
A patient taking warfarin is seen in the clinic today and prescribed a 2-Week course of fluconazole for a fungal infection. Before the patient receives the first dose of fluconazole, the pharmacotherapy specialist should ensure that:
- A. The fluconazole dose is administered at least 2 hours after the Warfarin dose.
- B. The warfarin dose is empirically increased during fluconazole therapy.
- C. An INR is obtained initially and monitored during fluconazole therapy.
- D. The fluconazole prescription is changed to ketoconazole.
Answer: C
NEW QUESTION 92
Using a new assay, the following readings for Drug X concentration in a blood sample are obtained: 45 ng/mL, 43 ng/mL, 45 ng/mL, 44 ng/mL, 45 ng/mL, and 45 ng/mL. The true concentration of the drug was reported as 65 ng/mL using the gold-standard assay.
On the basis of these data, the new assay should be characterized in which of the following categories?
- A. Precise but not accurate
- B. Accurate but not precise
- C. Neither accurate nor precise
- D. Both accurate and precise
Answer: A
NEW QUESTION 93
Initial efficacy data on an experimental drug in the United States are usually collected in:
- A. Phase trials.
- B. Phase IV trials.
- C. Phase trials.
- D. Phase III trials.
Answer: D
NEW QUESTION 94
A 69-year-old Woman with chronic liver disease treated with furosemide and potassium chloride for ascites and peripheral edema presents with weakness and fatigue. Her serum laboratory Values are:
* Sodium: 138 mEq/L
* Potassium: 2.6 mEq/L
* Glucose: 88 mg/dL
* BUN: 33 mg/dL
* Chloride: 101 mEq/L
* HCO3- 26 mEq/L
* Creatinine: 1.1 mg/dL
Attempts to increase her serum potassium over the next 48 hours include intravenous replacement (240 mEq over this period), without success. The current serum potassium concentration is 2.8 mEq/L. Which of the following is the most appropriate test to obtain for this patient?
- A. Urinary potassium
- B. Urinary sodium
- C. Serum antidiuretic hormone
- D. Serum magnesium
Answer: C
NEW QUESTION 95
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