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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 67-year-old patient is hospitalized for decompensated heart failure. The serum sodium concentration is 130 mEq/L on admission. Which of the following is the most appropriate approach to managing the patient's hyponatremia?

A) 0.9% NaCl 200 mL/h intravenously for 5 hours
B) Conivaptan 20 mg intravenously over 24 hours
C) Restriction of both sodium and fluids
D) 3% NaCl 50 mL/h intravenously for 5 hours

2. When low molecular weight heparin is prescribed, in which of the following patient populations would monitoring anti-factor-Xa levels be reasonable to consider?

A) Significant renal impairment
B) Protein C and Protein S deficiencies
C) Anticardiolipin antibody syndrome
D) Past history of GI bleeding

3. A 59-year-old patient who is HIV-positive is receiving darunavir and ritonavir as part of a highly active antiretroviral therapy program. Which herbal supplement is contraindicated for this patient because it would decrease darunavir concentrations?

A) Kava kava
B) St. John's wort
C) Echinacea
D) Saw palmetto

4. A 58-year-old man presents complaining of unsteady gait. Past medical history is significant for diabetes mellitus, gastroparesis, and depression. The patient exhibits a slight shuffling gait, mild limb rigidity, and decreased speed in performing rapid alternating movement. Current daily medications are bupropion, glyburide, metoclopramide, and omeprazole. Which of the following would be the most appropriate initial management for the presenting complaint?

A) Discontinue metoclopramide.
B) Begin ropinirole.
C) Begin carbidopa/levodopa.
D) Discontinue bupropion.

5. A 75 year old patient with a BP of 70/40 mm HR and HR of 35 bpm after CPR should FIRST receive which of the following intravenous medications?

A) Dopamine
B) Epinephrine
C) Atropine
D) Isoproterenol

Solutions: